Installtion
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Just put all the files into a directory of your choice. Make sure you have
.NET 4.0 Framework installed!
Set the folders in the Settings tab (for DA2: first one should be your
override folder, secondone whereever you want to store you packed mods).
Make sure the user running the Mod Manager has write permissions in both
folders!

Uninstall
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Delete the directory. To remove the settings as well, delete 
"%USERPROFILE%\AppData\Local\Mod_Manager" folder as well.